Rational Drug Design

Rational Drug Design

Thomas Mavromoustakos, Tahsin F. Kellici
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This volume covers several aspects of rational drug design, such as synthesis of novel bioactive drugs; development and application of new methodologies; computational methods valuable for the establishment of new approaches in drug discovery; and the effects of physical-chemical and ADMET properties of the designed potential drugs. Chapters guide readers through amyloid deposits, Saturation Transfer Difference (STD) NMR, methods on bioguided design, the importance of lipophilicity in drug design, ADMET, FRET, structural biology, and homology modeling. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Rational Drug Design: Methods and Protocolsaims to ensure successful results in the further study of this vital field.

Категории:
Година:
2018
Издание:
1st ed.
Издателство:
Springer New York;Humana Press
Език:
english
ISBN 10:
1493986309
ISBN 13:
9781493986309
Серия:
Methods in Molecular Biology 1824
Файл:
PDF, 13.63 MB
IPFS:
CID , CID Blake2b
english, 2018
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